Premenopausal women are more likely to suffer from depression and anxiety

Although many people think that menopause mainly affects the reproductive system, it is the brain that affects women the most. Progesterone binds, for example, to the receptors of GABA, which is a neurotransmitter, that is, a chemical messenger that transmits information from one nerve cell to another, regulates the nervous system, brings an anxiolytic effect, reduces anxiety and tension, because it offers a calming effect.

“When these receptors no longer receive the hormone, they end up losing use of it, and this can make a woman feel more anxious,” says Maria Klein, a psychologist who specializes in neuropsychology, anxiety and fear.

Psychological and physical symptoms of perimenopause

According to the expert, during perimenopause, women may experience a variety of mental health symptoms, including:

Researchers suggest that decreased estrogen levels during menopause may be a major factor in increased symptoms of depression. Estrogen affects the metabolism of neurotransmitters such as dopamine, norepinephrine, endorphins, and serotonin, all of which are involved in regulating emotional states. Therefore, a decrease in this hormone can lead to the emergence of new depressive symptoms or a worsening of existing symptoms.